Rosuvastatin 287714-41-4

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Product Details:

Poisonous NO
Usage Pharmaceutical formulation for hyperlipidemia and dyslipidemia
Storage Store in a cool, dry place, tightly closed container
Physical Form Powder
Ph Level Neutral
CAS No 287714-41-4
Smell Odorless
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Rosuvastatin 287714-41-4 Product Specifications

Properties Inhibits HMG-CoA reductase, lipid-lowering agent
Smell Odorless
Melting Point Not less than 120°C (dec.)
Application Cholesterol-lowering medication
HS Code 29420090
Poisonous NO
Usage Pharmaceutical formulation for hyperlipidemia and dyslipidemia
CAS No 287714-41-4
Ph Level Neutral
Storage Store in a cool, dry place, tightly closed container
Physical Form Powder
Taste Tasteless
Product Type Active Pharmaceutical Ingredient
Molecular Weight 1001.14 g/mol (calcium salt)
Shelf Life 3 years
EINECS No none assigned
Grade Pharmaceutical Grade
Molecular Formula C22H27FN3O6S.Ca
Ingredients Rosuvastatin Calcium
Purity >99% (HPLC)
Structural Formula [Refer to chemical structure]
Shape Crystalline solid
Solubility Soluble in DMSO, slightly soluble in water
Appearance White to off-white powder

Heavy Metals <10 ppm
Related Substances <0.5%
Packing HDPE drums or as per customer requirement
Stability Stable under recommended storage conditions
Standard USP/In-house Spec
Loss on Drying <0.5%
Therapeutic Category Lipid-lowering agent (statin)

Rosuvastatin 287714-41-4 Trade Information

Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Product Description

General description:

Chemical Formula: C22H28FN3O6S

Rosuvastatin, sold under the trade name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. It is recommended to be used together with dietary changes, exercise, and weight loss.

Application & Usage:Rosuvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood.

Packing25 Kg HDPE Drums

Pharmaceutical Grade Quality and Purity

Rosuvastatin calcium is supplied as a white to off-white, tasteless and odorless powder with a crystalline structure. Manufactured under USP or in-house specifications, it boasts over 99% purity (HPLC), low heavy metal content, and minimal related substances. These stringent quality measures ensure reliable performance in pharmaceutical formulations.

Primary Therapeutic Uses and Benefits

As a statin, Rosuvastatin effectively lowers cholesterol by inhibiting HMG-CoA reductase, a key liver enzyme. Its widely used in pharmaceutical preparations to manage high cholesterol (hyperlipidemia) and related lipid disorders. Its excellent stability and purity enhance therapeutic outcomes and ensure safety for end-users.

Optimal Packaging and Storage Conditions

Rosuvastatin is typically packed in HDPE drums or customized packaging as per specific client requirements. To maintain potency and longevity, it should be stored in a cool and dry environment in tightly closed containers. Proper storage safeguards its three-year shelf life and upholds product integrity.

FAQs of Rosuvastatin 287714-41-4:

Q: How does Rosuvastatin lower cholesterol levels?

A: Rosuvastatin works by inhibiting HMG-CoA reductase, a liver enzyme essential for cholesterol synthesis. This action decreases cholesterol production, effectively lowering LDL (bad) cholesterol and total cholesterol in the bloodstream.

Q: What is the primary usage of Rosuvastatin calcium?

A: Rosuvastatin calcium is mainly used in pharmaceutical formulations for the treatment and management of high cholesterol (hyperlipidemia) and dyslipidemia.

Q: When should Rosuvastatin be stored and how long is its shelf life?

A: Rosuvastatin should be stored in a tightly closed container in a cool, dry place to ensure stability. Under recommended conditions, it has a shelf life of up to three years.

Q: What is the process for ensuring the quality of Rosuvastatin supplied?

A: Quality is guaranteed by manufacturing Rosuvastatin to USP or in-house specifications, monitoring impurity levels, purity by HPLC (>99%), heavy metals content (<10 ppm), and related substances (<0.5%). All batches undergo rigorous analytical testing before shipment.

Q: Where is Rosuvastatin typically exported from and in what packaging?

A: Rosuvastatin is exported, supplied, and traded from India. It is generally packed in HDPE drums or as per customer requirements to ensure safe handling and storage.

Q: What are the benefits of using high-purity Rosuvastatin in pharmaceutical applications?

A: High-purity Rosuvastatin elevates therapeutic efficacy, minimizes impurities, and ensures patient safety. Its pharmaceutical grade quality makes it ideal for reliable and consistent cholesterol-lowering medications.

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